New Research Confirms HMB Benefits for Wide Range of Adults


There is mounting scientific evidence showing that HMB, typically used for muscle health, can benefit a wide range of adults. Two new comprehensive reviews confirm its benefits for everyone from older adults to endurance athletes.

“Muscle health nutrients were once almost exclusively the domain of sport nutrition. While that remains a very popular market, muscle nutrition for the healthy aging category is growing rapidly,” said Shawn Baier, vice president of business development at TSI Group (Shanghai, China). “Significantly, these new reviews focus on HMB’s value in relevant new areas within these two categories, and what these scientists found is both exciting and encouraging.”

Researchers from the Universidade Fernando Pessoa (Portugal) analyzed 14 diverse studies published in Topics in Clinical Nutrition. They noted more than half of those studied reported HMB supplementation improved muscle strength and other functional outcomes.

The researchers also added new and updated evidence not previously included in HMB reviews. They examined studies demonstrating the effects of HMB on physical functionality such as gait speed, time up and go (TUG) and short physical performance battery (SPPB) tests. The studied found improvements among the HMB groups in all these parameters.

“By 2030, it’s estimated there will be more than 1.4 billion older adults,” Baier said. “Age-related muscle loss will impact all of them, potentially putting even everyday activities out of reach.”

A second review published in the Journal of Strength and Conditioning Research, highlighted even more benefits for endurance athletes.

After reviewing 11 studies involving 279 participants, researchers concluded HMB ingestion produced significant improvements in endurance performance and VO2 max. They also noted HMB may enhance performance through mechanisms beyond VO2 max improvement including enhanced glycogen storage and post-training recovery.

“One of the most interesting aspects of this review is the discussion of how HMB improves physical performance potentially through different physiological pathways, including HMB’s impact on oxygen uptake (VO2 max) and time to exhaustion,” Baier said.

TSI also has its own HMB ingredient called myHMB that is clinically supported for many products including those related to active lifestyles, healthy aging, sport performance and body composition, the company said.

“TSI’s primary scientific investigations, combined with those of qualified researchers from throughout the world, have elevated HMB to a highly regarded muscle health supplement,” Baier said. “Reviews such as these reinforce and reinvigorate the research, because they underscore HMB’s tremendous potential.”

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